Njira yoyera ya arbutin
Zomwe zili ndi kugawa kwamelanin ndi zinthu zazikulu zomwe zimatsimikizira kuya kwa mtundu wa khungu. Melanin amapangidwa mu melanocyte mu basal wosanjikiza wa khungu epidermis. Amapangidwa pomaliza kuchokera ku tyrosine pansi pa zochita za tyrosinase kudzera muzotsatira zovuta zazachilengedwe. Amasamutsidwa kuchokera ku basal layer kupita kukunja kwa epidermis kuchokera mkati kupita kunja kudzera mu synapses. Lembani khungu.
Tyrosinase ili ndi ntchito ya tyrosine hydroxylase (yothandizira tyrosine kupanga dopa) ndi ntchito ya dopa oxidase (yothandizira dopa kupanga dopaquinone). Pakupanga melanin, imakhala ngati enzyme yayikulu yoletsa. Ntchito yake imatsimikizira kuchuluka kwa melanin.
Arbutin ndi tyrosinase inhibitor yomwe imatha kuletsa bwino ntchito ya tyrosinase popanda kukhudza kuchuluka kwa ma cell. Imapikisana kuti imangirire dopa kudzera pakumangiriza mwachindunji ku tyrosinase. malo, midadada kaphatikizidwe wa dopa ndi dopaquinone, potero kusokoneza melanocytes ndi kuletsa kupanga melanin. Pa nthawi yomweyo, alinso ntchito ya diluting anapanga melanin, imathandizira kuwonongeka ndi excretion melanin, kuchepetsa khungu pigmentation, ndi kuchotsa mawanga ndi mawanga.
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Nthawi yotumiza: Feb-23-2024
