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Ubale pakati pa resveratrol ndi thanzi laumunthu

2024-07-24 11:56:08

RESVERATROL

Resveratrol, non-flavonoid polyphenol organic compound, ndi antitoxin yopangidwa ndi zomera zambiri pamene ilimbikitsidwa, ndi mankhwala a C14H12O3. Ikhoza kupangidwa mu masamba a mphesa ndi zikopa za mphesa ndipo ndi bioactive pophika mu vinyo ndi madzi a mphesa.Resveratrolndipo zotumphukira zake zimapezeka makamaka mu mitundu 72 ya zomera mu 31 genera ndi mabanja 21 monga Vitis, Polygonum, chiponde ndi veratrol, kuphatikizapo mankhwala wamba mankhwala monga knotcane, cassia ndi mabulosi, komanso mbewu monga mphesa ndi mtedza. . Waukulu zachilengedwe magwero aresveratrolndi knotweed ndi mphesa.Resveratrolimatengeka mosavuta m'kamwa ndikutuluka mumkodzo ndi chopondapo pambuyo pa metabolism. Kuyesa kwa in vitro ndi nyama kwawonetsa iziresveratrolali ndi antioxidant, anti-yotupa, anticancer ndi mtima zoteteza zotsatira. Kufufuza mgwirizano pakatiresveratrolndipo thanzi la anthu ndiloyenera kulimbikitsa kukonzanso ndi kugwiritsa ntchito mozamaresveratrolndi kukonza thanzi la anthu.

MAPETO

Mayesero asonyeza kuti chisanadze alowererepo ndiresveratrolimatha kupewa kuwonongeka kwa chiwindi chifukwa cha iris. Nthawi yomweyo,resveratroladapezeka kuti amaletsa kutupa kwa chiwindi panthawi ya HIRI pokhudza ma neutrophils. The makina ameneresveratrolAmawongolera ma neutrophils ndikuletsa kupulumuka kwa neutrophils, kuzungulira kwa ma cell, kusamuka kwa chemotaxis, kupsinjika kwa okosijeni, kutulutsa kwa cytokine ndi endothelin-1 autocrine poletsa njira yolumikizira ya ERK. Deta iyi imapereka umboni wochulukirapo wa zotsatira za immunomodulatoryresveratrolndikulemeretsa kumvetsetsa kwathu njira zoteteza chitetezo ku HIRI.

Zolozera:

WANG YN, SUN XJ, HAN XT, et al.Resveratrolimathandizira kuvulala kwa hepatic ischemia-reperfusion poletsa ma neutrophils kudzera panjira yolumikizira ya ERK[J]. Biomedicine & Pharmacotherapy, 2023, 160: 114358. DOI:10.1016/j.biopha.2023.114358.

Kutengera maphunziro athunthu a preclinical,resveratrolimakhala ndi zotsatira za chemoprotective ndi chemosensitizing kudzera mu anti-plasticity, antioxidant, anti-inflammatory, ndi pro-apoptotic modes. Kuphatikiza pa zotsatira zake za anticancer,resveratrolimagwiranso ntchito ngati woyang'anira wa chemotherapy-induced toxicity m'maselo/minofu wamba. Monga mankhwala odana ndi chotupa (kutsata njira zingapo), kuphatikiza kwa mankhwala kumapangitsa kuti achire ake azigwira bwino ntchito kudzera mu superposition ndi synergy, komanso amachepetsa zotsatira za kukana kwa chemotherapy.

LUMIKIZANANI NAFE

Foni yam'manja: 86 18691558819
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Mwachidule, nkhaniyi ikuwunikiranso zotsatira za chemical sensitization zaresveratrolpa ma cell chotupa kupita ku mankhwala a chemotherapy kuchokera ku ma cell plasticity, omwe ndi ofunikira kwambiri pakusinthika kwa maselo kupita ku TME panthawi ya kusintha kwa maselo a chotupa ndi metastasis. Izi zimaperekanso chilimbikitso chatsopano pakufufuza kwina pa khansa ya epigenetics ndi resveratrol-mediated plasticity inhibition, kunena mwamphamvu kutiresveratrol, monga phytochemical yogwira ntchito, idzagwira ntchito popewa ndi kuchiza CRC m'tsogolomu. udindo wofunikira.

Kuti mudziwe zambirizambiriza malonda ndi ntchito zathu chonde titumizireni.

Zambiri:https://www.xahealthway.com/

Resveratrol:
https://www.xahealthway.com/polygonum-cuspidatum-extract-trans-resveratrol-98-hplc-product/