Lo Han GuoTingafinye ndi wotumbululuka chikasu ufa kuti bulauni Tingafinye. Imakoma kwambiri, imatsekemera kuwirikiza 240 kuposa sucrose, pafupi ndi shuga, yokhala ndi zokometsera pang'ono ngati licorice. Malo osungunuka a mogroside yoyera kwambiri ndi 197-201 ° C. Ndiwosavuta kusungunuka m'madzi ndi Mowa.
Ntchito:
1.Monk Zipatso Tingafinye(Mogroside) ntchito chikhalidwe Chinese mankhwala chimfine, chifuwa, zilonda zapakhosi, m`mimba kusapeza bwino, ndipo angagwiritsidwe ntchito kuyeretsa magazi.
2. Monk Fruit Extract (Mogroside) imasungunuka mosavuta m'madzi ndipo ilibe mvula.
3. Mogroside ili ndi kuchuluka kwa amino acid, fructose, mavitamini ndi mchere. Amagwiritsidwanso ntchito pophika achi China ngati zokometsera komanso zowonjezera zakudya. Monga chotsekemera chachilengedwe chonse, ndi cholowa m'malo mwa zotsekemera zopanga monga aspartame. Itha kugwiritsidwa ntchito muzakumwa, zowotcha, zakudya zopatsa thanzi, zakudya zokhala ndi ma calorie ochepa kapena zakudya zina zomwe zimafuna zotsekemera zamafuta ochepa kapena zosakhala ndi ma carbohydrate kapena zopatsa mphamvu zochepa kapena zopanda mphamvu. Kuphika kapena kuphika sikukhudza kukoma kwake kapena kukoma kwake.
Zotsatira za Pharmacological
(1) Expectorant zotsatira: Mogroside (okwana glycosides> 80%) 0.2g/kg, 0.4g/kg, 0.8g/kg anali kutumikiridwa intragastric. Mlingo wa 0.4g / kg ndi 0.8g / kg udachulukitsa kwambiri kuchuluka kwa zotulutsa zam'mimba mu makoswe, zomwe zikuwonetsa zotsatira zazikulu za expectorant.
(2) Kuchotsa m'mapapo ndi antitussive zotsatira: Mogroside (chiwerengero cha glycosides> 80%) 0.2g/kg, 0.4g/kg, 0.8g/kg chinachepetsa kwambiri chifuwa cha mbewa zochititsidwa ndi ammonia, koma sichinakhudze kwambiri nthawi yoyambitsa chifuwa cha ammonia.
(3) Kusakaza kwaulere komanso zotsatira za antioxidant:
a.Mogroside kuchotsa(Mogroside) (chiwerengero cha glycosides ≥ 98%, Mogroside V okhutira 65.20%) ali ndi vuto linalake la hydroxyl free radicals ndi superoxide anion free radicals. Ndi kuwonjezeka kwa ndende ya Mogroside Tingafinye, ndi mkangaziwisi zotsatira pang'onopang'ono kumawonjezera, kusonyeza ena mlingo-zotsatira ubale;
b. Mogroside Tingafinye ali kwambiri inhibitory zotsatira za okosijeni hemolysis anachita makoswe RBC pa m`galasi makulitsidwe. Pakati pa 0.04-1.15 mg/ml, kuletsa kwa Mogroside Tingafinye pa erythrocyte autooxidative hemolysis ndi oposa 50%, ndi Mogroside Tingafinye ali ndi zabwino zoteteza zotsatira RBC autooxidative hemolysis;
c. Chitetezo chochokera ku Mogroside pa RBC autooxidative hemolysis sichiwonetsa ubale wa zotsatira za mlingo. Mlingo wabwino kwambiri ndi 0.46 mg/ml, ndi chiletso cha 85.55%;
d. Malondialdehyde (MDA) ndi gawo lomaliza la lipid peroxidation ndipo lingagwiritsidwe ntchito kuyesa mphamvu ya lipid peroxidation. Mogroside Tingafinye ali amphamvu inhibitory zotsatira kupanga MDA pa makoswe erythrocyte autooxidation hemolysis;
ndi.Mogroside kuchotsaali ndi zotsatira zabwino zoletsa pakupanga mowiriza wa MDA mu makoswe chiwindi homogenate. Zotsatira zoletsa zimakhala bwino kwambiri pamagulu a 0,875 mg/ml, kufika 23.63%; f. Mogroside Tingafinye zingalepheretse zamadzimadzi peroxidation mu makoswe chiwindi minofu, ali ndi zoteteza chiwindi minofu peroxidation kuwonongeka anachititsa ndi Fe ndi H2O2, ndipo akhoza kuchepetsa zimachitika erythrocyte hemolysis; Mogroside imatha kuletsa kwambiri kupanga kwa MDA mu mitochondria ya chiwindi, ndipo kuletsa kwake kumawonjezeka ndi kuchuluka kwa ndende.
(4) Kuonjezera chitetezo:
Oral administration ya mogroside to normal and cyclophosphamide (CTX) -oponderezedwa mbewa sizinakhudze kwambiri chitetezo cha mbewa zabwinobwino, koma zinasintha kwambiri macrophage phagocytosis ndi T cell kuchuluka kwa mbewa zoponderezedwa ndi CTX. Izi zikuwonetsa kuti mogroside ili ndi mphamvu ina yoyendetsera chitetezo cham'manja cha mbewa zoponderezedwa ndi CTX.
(5) Mmene shuga wamagazi:
A limodzi m`kamwa makonzedwe a 30% mogroside 200 mg/kg analibe kwambiri zotsatira za shuga wokhutira ndi chiwindi enzyme ntchito athanzi achikulire.MogrosideV ndi zotsekemera zotetezeka zomwe sizikhudza kuchuluka kwa shuga m'magazi mwa anthu abwinobwino.
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(6) Anti-cancer effect:
Pogwiritsa ntchito DMBA monga woyambitsa ndi TPA monga carcinogen, kuyesa kwa mbewa kwa magawo awiri a carcinogenicity kunachitika; kuchedwa kwa carcinogenicity ya mogroside ndi yofanana kapena yamphamvu kuposa ya stevioside, kusonyeza kuti ili ndi zotsatira zotsutsana ndi khansa. Choncho, mogroside angagwiritsidwe ntchito ngati wothandizira khansa.
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Nthawi yotumiza: Aug-23-2024
